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How Long Do Sars-Cov-2 Antibodies Last?

As the COVID-19 pandemic transitions towards an endemic state, questions loom around potential reinfections and immunity duration after either vaccination or recovery from SARS-CoV-2. Unpacking the nuances around antibody persistence and immunological memory remains critical. While antibody levels measurable in blood may wane months after initial infection, does this mean protection vanishes? Or might elements of our immune system retain imprints enabling rapid response upon re-exposure? Understanding these dynamics informs public health policy and personal risk assessment. The Crucial Early Antibody Response Neutralizing antibodies circulate through blood and mucosa as sentinels on guard against repeat SARS-CoV-2 attack. Their early emergence represents the first line of adaptive defense trying to block viral attachment and entry into host cells. Potent neutralizing antibodies directly correlate with protection against progression to severe COVID-19. But depending on disease seve